Growth hormone deficiency in children with chromosomal abnormalities.
نویسندگان
چکیده
منابع مشابه
Growth hormone deficiency in children with chromosomal abnormalities.
Growth hormone deficiency in children with chromosomal abnormalities SIR,-I read with some surprise the letter by Schwartz and Duck on the treatment with growth hormone of two children with chromosome deletions associated with multiple mal-formations, microcephaly, and mental handicap.' Though I too am intrigued that a cause of poor growth in some children with chromosome disorders might be med...
متن کاملMetabolic abnormalities in growth hormone deficiency.
Growth hormone has been implicated in the regulation of cardiovascular function and growth hormone deficiency (GHD) has been postulated to be one of the main factors responsible for the increased morbidity and mortality from cardiovascular disease in both young and older patients with childhood- and adulthood-onset GHD. Growth hormone also influences bone turnover and mineral deposition. Subjec...
متن کاملNeuroanatomical associates of the cognitive and motor abnormalities found in children with Isolated Growth Hormone Deficiency
Introduction: While growth hormone (GH) plays an important role in normal brain development, its effect on brain growth and cognition in GH deficient individuals continues to be debated. We have now investigated a cohort of children with isolated growth hormone deficiency (IGHD) using cognitive and motor skills assessment, volumetric MRI and diffusion tensor imaging (DTI) and compared the findi...
متن کاملNovel Growth Hormone-Releasing Hormone Receptor Gene Mutations in Turkish Children with Isolated Growth Hormone Deficiency
OBJECTIVE Isolated growth hormone deficiency (IGHD) is defined as a medical condition associated with growth failure due to insufficient production of GH or lack of GH action. Mutations in the gene encoding for GH-releasing hormone receptor (GHRHR) have been detected in patients with IGHD type IB. However, genetic defects on GHRHR causing IGHD in the Turkish population have not yet been reporte...
متن کاملChanges on craniofacial structures in children with growth-hormone-deficiency.
OBJECTIVE To describe the growth of craniofacial structures in growth-hormone deficiency (GHD) children during growth-hormone therapy (GHT). METHODS A cross-sectional sample of 46 subjects (n = 14 girls, 32 boys) aged 4-18 years was obtained. They were categorized into two paired groups: the reference group, for comparing the cephalograms, consisted in 23 healthy subjects, and the study group...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1990
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.65.10.1183